Startups in LA are gaining traction, with more billion-dollar companies emerging there than in New York in recent years.

Silicon Valley's understanding of blockchain technology has lagged behind other regions, with many innovative ideas and projects emerging from New York and Europe.

The current funding landscape has seen a decline in local market-focused startups, with less emphasis on replicating successful U.S. models in international markets.

Choosing New York over Silicon Valley has allowed us to focus more on real-world problems rather than getting caught up in the tech echo chamber, which has been beneficial for our business.

San Francisco is unique in that it celebrates the challenges of starting a company, creating an environment where entrepreneurs feel understood and supported.

Starting a company in Europe presents challenges, such as a fragmented market and a lack of nurturing environments for early-stage startups compared to Silicon Valley.

The network in Silicon Valley is crucial for startups, providing opportunities for collaboration and support that are hard to find elsewhere.

The agglomeration of talented individuals in San Francisco fosters innovation and the creation of impactful companies.

There's a significant gap in funding for early-stage biotech discoveries, leading many companies to apply to Y Combinator when they have initial data suggesting a promising approach to curing diseases.