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Bob McGrew

06/17/25

@ Sequoia Capital

Startups should focus on areas where deep understanding outside of the model is necessary, as these are safer spaces to operate without being overshadowed by larger labs.

Video

The Breakthroughs Needed for AGI Have Already Been Made: OpenAI Former Research Head Bob McGrew

@ Sequoia Capital

The Breakthroughs Needed for AGI Have Already Been Made: OpenAI Former Research Head Bob McGrew

06/17/25

Related Takeaways

Bob McGrew

06/17/25

@ Sequoia Capital

Enterprise applications often require a deep understanding of specific business contexts, which is where startups can find opportunities that larger labs may overlook.

Y Combinator Cast

06/07/24

@ Y Combinator

Startups should focus on building valuable but less glamorous products that larger companies like OpenAI won't prioritize.

Mike Krieger

06/05/25

@ Lenny's Podcast

AI startups should focus on niche markets and specific applications to avoid being overshadowed by larger companies like OpenAI and Google.

Y Combinator Cast

06/07/24

@ Y Combinator

Startups should focus on building the best products on top of existing AI models, as competition will come from other startups rather than the AI giants themselves.

Harvard Innovation Labs Cast

06/12/13

@ Harvard Innovation Labs

Startups should focus on a narrow market segment initially to avoid overwhelming themselves and to build a solid foundation for growth.

Bob McGrew

06/17/25

@ Sequoia Capital

The frontier labs tend to focus on training models for new tasks, while many enterprise problems are too small for them to address individually, creating opportunities for startups.

Y Combinator Cast

05/31/24

@ Y Combinator

The advice to do things that don't scale is counterintuitive but provides startups with a unique advantage over larger competitors by fostering deep customer understanding and rapid experimentation.

Sam Altman

06/01/17

@ Y Combinator

Startups should focus on solving problems as they arise rather than trying to preemptively address issues that may not be relevant at their current stage of growth.

Dalton Caldwell

03/22/24

@ Y Combinator

Founders should focus on areas where they have personal experience and knowledge, rather than relying solely on investor frameworks for assessing opportunities.