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Dr. Melissa Ilardo

05/26/25

@ Andrew Huberman

Diet is a strong driver of natural selection, as seen in populations like the Greenlandic Inuit, who evolved to metabolize high lipid content from marine mammals, impacting their health and survival.

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Behaviors That Alter Your Genes to Improve Your Health & Performance | Dr. Melissa Ilardo

@ Andrew Huberman

Behaviors That Alter Your Genes to Improve Your Health & Performance | Dr. Melissa Ilardo

05/26/25

Related Takeaways

Dr. Justin Sonnenburg

03/07/22

@ Andrew Huberman

Human genetic adaptation to diet is fascinating, as seen in the example of lactase persistence, where certain populations have adapted to digest dairy throughout their lives.

Christopher Gardner

05/12/25

@ Andrew Huberman

There isn't one best diet; humans are incredibly resilient and can thrive on various dietary patterns, as evidenced by the diverse diets of the Tarahumara Indians and Alaskan Inuits.

Elizabeth Iorns

09/14/17

@ Y Combinator

Individual responses to dietary interventions vary significantly, suggesting that personalized nutrition could be key to effective weight management and health outcomes.

Dr. Justin Sonnenburg

03/07/22

@ Andrew Huberman

Dietary changes can lead to rapid shifts in the gut microbiome, but it often returns to a state similar to its original condition, demonstrating resilience.

Chris Palmer

03/31/25

@ Andrew Huberman

Dietary interventions can dramatically change lives, but they should be part of a broader approach that includes various lifestyle factors.

Dr. Melissa Ilardo

05/26/25

@ Andrew Huberman

Natural selection can act on pregnant women, influencing two generations if genetic variation is not protective, which highlights the rapid evolution occurring in populations like the Henyo.

Dr. Justin Sonnenburg

03/07/22

@ Andrew Huberman

The gut microbiome is critical for modulating our immune status, and changes in diet can fundamentally alter how the immune system operates, potentially reducing inflammation and disease risk.

Chris Palmer

03/31/25

@ Andrew Huberman

Nutrition plays a profound role in human metabolism, impacting mental health outcomes, especially in early life, such as breastfeeding's effect on brain development.

Andrew Huberman

04/03/25

@ Andrew Huberman

Maintaining a low insulin level is beneficial for fat oxidation, and various dietary approaches can help achieve this, including low or moderate carbohydrate diets.