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Dr. Justin Sonnenburg

03/07/22

@ Andrew Huberman

Cleanses and fasting lack high-quality scientific backing, making it difficult to determine their health benefits or risks, especially in the context of a highly processed diet.

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How to Build, Maintain & Repair Gut Health | Dr. Justin Sonnenburg

@ Andrew Huberman

How to Build, Maintain & Repair Gut Health | Dr. Justin Sonnenburg

03/07/22

Related Takeaways

Dr. Justin Sonnenburg

03/07/22

@ Andrew Huberman

Cleansing or fasting before attempting to repopulate the microbiome is not necessary, as studies have not shown these practices to be beneficial or effective.

Chris Palmer

03/31/25

@ Andrew Huberman

Fasting has been part of healing rituals across cultures for thousands of years, suggesting its potential health benefits are recognized historically.

Dr. Justin Sonnenburg

03/07/22

@ Andrew Huberman

Short-term fasting may have metabolic benefits, but its long-term effects on gut microbiota health are still unclear, and excessive mucus consumption by microbes can lead to inflammation.

Elizabeth Iorns

09/14/17

@ Y Combinator

Fasting can improve metabolic control and appetite regulation, but it can be difficult to maintain, as it affects cognitive function during the fasting period.

Chris Palmer

03/31/25

@ Andrew Huberman

Fasting mimicking diets, like those developed by Valter Longo, can provide health benefits similar to ketogenic diets without the need for strict adherence to a ketogenic regimen.

Justin Kan Cast

05/27/21

@ Justin Kan

Fasting could be a societal solution to improve self-control, but it's not a scalable answer for everyone.

Dr. Justin Sonnenburg

03/07/22

@ Andrew Huberman

Rapidly fermentable fibers can lead to negative metabolic effects when combined with a Western diet, potentially increasing health risks.

Christopher Gardner

05/12/25

@ Andrew Huberman

Michael Pollan highlights the vast variety of diets that can support health globally, except for the standard American diet, which is largely unhealthy due to its processed nature.

Christopher Gardner

05/12/25

@ Andrew Huberman

Processed foods often contain additives and dyes that may not be beneficial for health, and it's essential to distinguish between different types of processed foods.