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Atmrix

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AH

Alex Hutchinson

05/04/25

@ Chris Williamson

There's a genetic mutation linked to the desire to explore, specifically the DRD4 dopamine receptor, which makes some people more sensitive to novelty.

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How To Rewire Your Brain To Take More Risks - Alex Hutchinson

@ Chris Williamson

How To Rewire Your Brain To Take More Risks - Alex Hutchinson

05/04/25

Related Takeaways

AH

Alex Hutchinson

05/04/25

@ Chris Williamson

Dopamine doesn't just signal pleasure; it provides a hit when something exceeds our expectations, driving us to explore and seek new experiences.

AH

Andrew Huberman

05/28/25

@ Theo Von

The dopamine system loves surprise; when an experience exceeds expectations, dopamine levels rise significantly.

AH

Andrew Huberman

05/28/25

@ Theo Von

Dopamine is involved in motivation, driving us to move towards something we desire.

AH

Andrew Huberman

01/30/25

@ Andrew Huberman

There's a fundamental relationship between dopamine release in the brain and the desire to exert effort; understanding this system can help you leverage it to your benefit.

AH

Andrew Huberman

01/30/25

@ Andrew Huberman

Dopamine drives cravings and motivation, while serotonin and endocannabinoids help enhance enjoyment of the present, creating a balance between seeking more and appreciating what you have.

DA

Dr. Anna Lembke

08/16/21

@ Andrew Huberman

The anticipation of drug use creates a mini spike in dopamine, which is followed by a deficit state that drives the motivation to seek the drug.

AH

Andrew Huberman

05/28/25

@ Theo Von

Dopamine is triggered by anticipation of something, not just the experience itself.

AH

Andrew Huberman

06/19/25

@ Andrew Huberman

Excessive dopamine release can lead to habituation, where the brain becomes less responsive to pleasure, while simultaneously increasing the perception of pain, a mechanism that can contribute to addiction.

AH

Andrew Huberman

01/30/25

@ Andrew Huberman

Dopamine is primarily released in anticipation and craving rather than in response to pleasure, which narrows our focus on what we desire.