To increase dopamine release, one can practice subjective rewards through thoughts, actions, or even certain drugs, but caution is needed with substances like cocaine and methamphetamine due to their addictive nature.

Triggers that make us want to return to drug use also release dopamine, leading to cravings when the anticipation of using is followed by a dopamine deficit state.

Excessive dopamine release can lead to habituation, where the brain becomes less responsive to pleasure, while simultaneously increasing the perception of pain, a mechanism that can contribute to addiction.

Addiction is not just about pleasure; it's about wanting and motivation, which is driven by dopamine deficits.

The anticipation of drug use creates a mini spike in dopamine, which is followed by a deficit state that drives the motivation to seek the drug.

When people change their emotional states, they often experience cravings similar to overcoming any addiction, which can be challenging.

Stimulants like cocaine and amphetamines can deplete mitochondria, leading to long-term health issues, while appropriate doses of stimulants can improve brain metabolism in individuals with ADHD.

People with severe addiction often seek extreme highs and lows, which can lead to an addiction to the recovery community itself.

Dopamine drives cravings and motivation, while serotonin and endocannabinoids help enhance enjoyment of the present, creating a balance between seeking more and appreciating what you have.