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Andrew Huberman
08/22/22
@ Andrew Huberman
In cultures with higher alcohol dehydrogenase levels, individuals can drink more without feeling sick, which can lead to higher rates of alcoholism due to increased consumption.
Video
AH
What Alcohol Does to Your Body, Brain & Health
@ Andrew Huberman
08/22/22
Related Takeaways
AH
Andrew Huberman
08/22/22
@ Andrew Huberman
Regular drinkers or those with a genetic predisposition to alcoholism may experience increased alertness and mood when consuming alcohol.
AH
Andrew Huberman
08/22/22
@ Andrew Huberman
Genetic predispositions, combined with environmental factors, contribute to the likelihood of developing alcohol use disorders. Certain Asian cultures have genetic differences that lead to low levels of alcohol dehydrogenase, causing individuals to feel sick and flushed when they consume alcohol.
AH
Andrew Huberman
08/22/22
@ Andrew Huberman
Regular alcohol consumption can lead to inflammation in the brain and body, increasing the desire to drink more and exacerbating health issues.
AH
Andrew Huberman
08/22/22
@ Andrew Huberman
If you feel nauseous after consuming alcohol, you likely have gene variants that result in low alcohol dehydrogenase levels, preventing you from metabolizing alcohol effectively.
AH
Andrew Huberman
08/22/22
@ Andrew Huberman
Tolerance to alcohol develops as repeated exposure reduces its effects, leading to increased consumption to achieve the same feeling of well-being.
AH
Andrew Huberman
08/22/22
@ Andrew Huberman
Genetic differences can predispose individuals to alcoholism and affect how they metabolize alcohol, especially in young people.
DS
Dr. Sarah Wakeman
05/22/25
@ The Diary Of A CEO
People metabolize alcohol at different rates, which can affect their hangover severity and overall health risks associated with drinking.
DS
Dr. Sarah Wakeman
05/22/25
@ The Diary Of A CEO
Moderate to high alcohol consumption tends to cause liver damage, with binge drinking being more harmful than moderate drinking over a longer period.
DS
Dr. Sarah Wakeman
05/22/25
@ The Diary Of A CEO
Heavy alcohol use can lead to brain damage, with ethanol causing inflammation and nutritional deficiencies that accelerate deterioration.