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Andrew Huberman

04/03/25

@ Andrew Huberman

Compounds like berberine and metformin can lower blood glucose and insulin levels, which in turn can increase fat oxidation by reducing insulin's inhibitory effect on fat metabolism.

Video

Lose Fat With Science-Based Tools | Huberman Lab Essentials

@ Andrew Huberman

Lose Fat With Science-Based Tools | Huberman Lab Essentials

04/03/25

Related Takeaways

Andrew Huberman

04/03/25

@ Andrew Huberman

Maintaining a low insulin level is beneficial for fat oxidation, and various dietary approaches can help achieve this, including low or moderate carbohydrate diets.

Andrew Huberman

04/03/25

@ Andrew Huberman

Certain compounds can enhance fat oxidation and mobilization, which is beneficial for accelerating fat loss, particularly those that increase epinephrine release.

Andrew Huberman

04/03/25

@ Andrew Huberman

Fasted exercise can enhance fat oxidation, especially after about 90 minutes of moderate-intensity exercise, where the body shifts from burning glycogen to body fat.

Andrew Huberman

04/03/25

@ Andrew Huberman

Yerba maté increases GLP-1 levels, which facilitates fat mobilization and enhances fat burning, especially when consumed before exercise.

Dr. Mark Hyman

04/14/25

@ Andrew Huberman

Insulin resistance can lead to abnormal cholesterol levels, affecting both LDL and HDL. It's important to monitor these levels and understand their implications for cardiovascular health.

Dr. Sarah Wakeman

05/22/25

@ The Diary Of A CEO

Obesity and diet significantly impact liver health, as the liver is involved in glucose metabolism.

Elizabeth Iorns

09/14/17

@ Y Combinator

Fasting can improve metabolic control and appetite regulation, but it can be difficult to maintain, as it affects cognitive function during the fasting period.

David Zeevi

08/22/18

@ Y Combinator

In our study with 26 participants, we designed diets to either reduce or increase blood glucose levels, demonstrating that personalized diets can effectively manage glucose responses.

David Zeevi

08/22/18

@ Y Combinator

Blood glucose spikes after eating carbohydrates lead to insulin secretion, which signals the body to store glucose as fat, contributing to weight gain and various metabolic diseases.